Pancreatin is a combination of digestive enzymes normally produced by the pancreas and are important for digesting fats, proteins, and sugars. Pancreatin is used to replace digestive enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, such as cystic fibrosis, pancreatitis, pancreatic cancer, or pancreas surgery. Pancreatin may also be used to treat a condition called steatorrhea (loose, fatty stools). it may be used for indigestion, as a supplement, or as replacement therapy. Pancreatic enzymes such as pancreatin have been used as medications since at least the 19th century and are on the World Health Organization's List of Essential Medicines